In gene therapy, which of these non-viral DNA delivery methods requires endocytosis?

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Correct Answer: B. Dendrimer delivery.
DNA injection, electroporation, magnetofection and sonoporation are all examples of physical methods used to deliver DNA non-virally. The use of dendrimers on the other hand is considered a chemical method of DNA delivery, whereby cationic dendrimers are temporarily associated with DNA until endocytosis takes place, where DNA can subsequently be released from the dendrimer.
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