Curare is a chemical used in arrow poisons as well as in pharmaceutical compounds. It competes with acetylcholine for receptor sites along the motor end plate. The immediate physiological effects of high doses of curare can include:
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Correct Answer:
B. Inability to contract muscles and paralysis.
If curare competes with acetylcholine along the motor end plate (at the neuromuscular junction), ACh cannot perform its function. ACh normally causes skeletal muscles to depolarize and contract. If the is blocked, B is clearly the correct choice. Choices A and C refer to events after depolarization has taken place. Heat production results from contraction, which requires ACh in the first place.
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