
Human blood types are most often examined in reference to the ABO gene locus. The IA and IB alleles are both dominant to the i allele. If blood from a type AB individual were donated to three individuals who were, respectively, types A, B and O, which of the recipients blood would agglutinate?

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Correct Answer:
D. All of the recipients.
The A and B antigens on the red blood cells donated from the Type AB donor will be agglutinated by anti-B in the plasma of the Type A recipient, anti-A (in the Type B recipient), and both anti-A and anti-B (in the Type O recipient). Type AB donors are universal acceptors, but Type O are universal donors.
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